Modern Drug discovery includes screening hit identification, medicinal chemistry, and affinity, selectivity(to reduce the potential for side effects), efficacy, metabolic stability (toextend half-life), and oral. Includes optimization of those hits to determine for increased bioavailability
Screening methods based on phenotypic Drug detection have been used to discover new natural products mainly of terrestrial origin.Examples of exploring marine natural products are provided. The Future Trends section provides a comprehensive overview of recent advancements that will benefit the Pharmaceutical industry.